Rebuilding Nerve Tissue Not Just Bridging the Gap
LDP-916 is a first-in-class peptide hydrogel therapy that regenerates nerve tissue and restores function in PNI & SCI.
Maxonis is advancing a breakthrough regenerative therapy designed to restore meaningful motor and sensory function in areas of high unmet need.
Restoring nerve function
One of medicine’s greatest unmet needs
Why it matters?
200M+ patients live with nerve-related disabilities
Current solutions are limited, invasive, or non-regenerative
Patients suffer lifelong pain, loss of function and independence
The Opportunity
Peripheral Nerve Injury (PNI)
Spinal Cord Injury (SCI)
Future expansion into Traumatic Brain Injury (TBI)
LDP-916
A first-in-class peptide–hydrogel therapy that rebuilds nerve tissue.
Activates intrinsic nerve-repair pathways
Supports guided regeneration
Enables meaningful motor & sensory recovery
PNI - Peripheral Nerve Injury
Injected into a standard nerve tube during routine repair.
Supports recovery across gap sizes
Enables earlier sensory + motor return
Regenerative support for long-gap injuries
SCI - Spinal Cord Injury
Injected directly at the injury site.
Active in acute & chronic preclinical models
Promotes rebuilding of damaged neural tissue
Supports restoration of motor function
How it works
LDP-916 drives activation, guidance, and restoration through the regeneration process

Activation
LDP-916 activates the body’s natural nerve – repair cells, kick-starting the regeneration process

Guidance
The hydrogel creates a supportive environment that guides new nerve fibers across the injury

Restoration
As nerves reconnect, they regain their protective insulation and restore movement and sensation
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